Acetylcysteine is indicated for the treatment of mucous formation and accumulation in the lungs and acetaminophen overdose. Acetylcysteine as mucolytic agent – The viscosity of mucous secretions in the lung depends on the concentrations of protein and to a lesser extent deoxyribonucleic acid (DNA). The latter increases with increasing puss caused by cellular debris. The mucolytic action of acetylcysteine is related to the sulfhydryl group in the molecule. This group probably “opens” disulfide linkages in mucous thereby lowering the viscosity.
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